I Wish I Were a Mutant…

Oh man–talk about winning the genetic lottery: science has discovered a genetic mutation in some human beings that allows them to function on far less sleep than average.

Researchers have found a genetic mutation in two people who need a mere 6 hours of sleep a night. The finding, published in the Friday issue of Science, marks the first time scientists have identified a genetic mutation that relates to sleep duration in any animal or human. The discovery could open the door to understanding human sleep patterns and lead to treatments for insomnia and other sleep disorders.

Although the mutation has been identified in only two people, the power of the research stems from the fact that the shortened sleep effect was replicated in mouse and fruit-fly studies. As a result, the research now gives scientists a clearer sense of where to look for genetic traits linked to sleep patterns.

The gene mutation was found by scientists at the University of California, San Francisco, who were conducting DNA screening on several hundred blood samples from people who had taken part in sleep studies.

The scientists were searching the samples for variations in several genes thought to be related to the sleep cycle. In what amounts to finding a needle in a haystack, they spotted two DNA samples with abnormal copies of a gene called DEC2, which is known to affect circadian rhythms. They then worked back to find out who provided the samples and found a mother and daughter who were naturally short sleepers. The women routinely function on about 6 hours of sleep a night; the average person needs 8 to 8.5 hours of sleep.

When scientists bred mice with the same mutation, the animals slept less and recovered quicker from periods of sleep deprivation compared with regular mice.

What distinguishes the two women in the study and other naturally short sleepers is that they go to bed at a normal time and wake up early without an alarm. The two women, one in her 70s and the other in her 40s, go to bed around 10 or 10:30 at night and wake up alert and energized around 4 or 4:30 in the morning.

Our bodies, we’re always told, need 8 to 8.5 hours of sleep a night. Could you imagine how much you could get done in a day if you woke up rested and alert at 4:30am every day? I’d have like 3 extra hours a day to write before I had to do anything else…

The genetic mutation appears to be rare, though. Out of 70 families with known sleep problems studied at the university, only one family carried the mutation. The study suggests fewer than 5 percent of people appeared to be naturally short sleepers.

One of the researchers on the study said her “fantasy” was that the finding might eventually lead to a safe treatment for people who wanted or needed more awake hours and were looking for a way to get by on less sleep without harming their health.

How awesome would that be? Because as it is, I think I suffer from the opposite genetic trait: I think I’m in the 5 percent of people who need like 10 hours a night to function and feel human in the morning…

– S.

While My Guitar Gently Weeps: Les Paul, 1915-2009


I was saddened today by news of the death of Les Paul, pioneer of both the solid-body electric guitar and multi-track recording. He was 94.

While he was a jazz and country guitarist by inclination, Les Paul’s semi-hollow body and later solid body guitars (especially the line of Gibson and Epiphone electrics that bear his name) became a mainstay of rock and roll. They have been played by everyone from Jimmy Page and Eric Clapton to Slash and Lenny Kravitz. My own short-lived first job (4-months at McDonald’s) was undertaken with the sole intention of buying my own electic guitar, a Les Paul Custom.


His name is Zaphod…

But more than his inventive and musical accomplishments, you know what always impressed me about Les Paul?

He once broke his right arm and elbow; doctors told him that the nature of the break meant he would never again be able to bend his arm. Rather than moan about permanent disfigurment he simply asked the doctor to set his right arm–his picking arm–at a 90-degree angle so he could continue to play his guitar.

They don’t make ’em like that any more.

The AP obituary follows.

– S.

=-=-=-=-=-=-=-=-=-=-=

Guitar legend-inventor Les Paul dies at age 94
By LUKE SHERIDAN (AP)

WHITE PLAINS, N.Y. — Les Paul, who pioneered the solid-body electric guitar later wielded by a legion of rock ‘n’ roll greats, died Thursday of complications from pneumonia. He was 94. According to Gibson Guitar, Paul died at White Plains Hospital. His family and friends were by his side.

As an inventor, Paul also helped bring about the rise of rock ‘n’ roll with multitrack recording, which enables artists to record different instruments at different times, sing harmony with themselves, and then carefully balance the tracks in the finished recording.

The use of electric-amplified guitars gained popularity in the mid-to-late 1940s, and then exploded with the advent of rock in the mid-’50s.

“Suddenly, it was recognized that power was a very important part of music,” Paul once said. “To have the dynamics, to have the way of expressing yourself beyond the normal limits of an unamplified instrument, was incredible. Today a guy wouldn’t think of singing a song on a stage without a microphone and a sound system.”

“Without Les Paul, we would not have rock and roll as we know it,” said Terry Stewart, president of the Rock and Roll Hall of Fame and Museum. “His inventions created the infrastructure for the music and his playing style will ripple through generations. He was truly an architect of rock and roll.”

A tinkerer and musician since childhood, he experimented with guitar amplification for years before coming up in 1941 with what he called “The Log,” a four-by-four piece of wood strung with steel strings. He felt a solid body would give the instrument a different sound from a traditional hollow guitar with an electrical pickup added to it.

“I went into a nightclub and played it. Of course, everybody had me labeled as a nut.” He later put the wooden wings onto the body to give it a tradition guitar shape.

Leo Fender’s Broadcaster was the first mass-produced solid body electric on the market in the late 1940s. In 1952, Gibson Guitars began production on the Les Paul guitar.

Pete Townshend of the Who, Steve Howe of Yes, jazz great Al DiMeola and Led Zeppelin’s Jimmy Page all made the Gibson Les Paul their trademark six-string.

Over the years, the Les Paul series has become one of the most widely used guitars in the music industry. In 2005, Christie’s auction house sold a 1955 Gibson Les Paul for $45,600.

Guitarist Joe Satriani called Paul “the original guitar hero,” saying: “Les Paul set a standard for musicianship and innovation that remains unsurpassed.”

In the late 1960s, Paul retired from music to concentrate on his inventions. His interest in country music was rekindled in the mid-’70s and he teamed up with Chet Atkins for two albums. The duo were awarded a Grammy for best country instrumental performance of 1976 for their “Chester and Lester” album.

With Mary Ford, his wife from 1949 to 1962, he earned 36 gold records for hits including “Vaya Con Dios” and “How High the Moon,” which both hit No. 1. Many of their songs used overdubbing techniques that Paul had helped develop.

“I could take my Mary and make her three, six, nine, 12, as many voices as I wished,” he recalled. “This is quite an asset.” The overdubbing technique was highly influential on later recording artists such as the Carpenters.

Released in 2005, “Les Paul & Friends: American Made, World Played” was his first album of new material since those 1970s recordings. Among those playing with him: Peter Frampton, Jeff Beck, Eric Clapton and Richie Sambora.

“They’re not only my friends, but they’re great players,” Paul told The Associated Press. “I never stop being amazed by all the different ways of playing the guitar and making it deliver a message.”

Two cuts from the album won Grammys, “Caravan” for best pop instrumental performance and “69 Freedom Special” for best rock instrumental performance. (He had also been awarded a technical Grammy in 2001.)

Paul was inducted into the National Inventors Hall of Fame in 2005.

Paul was born Lester William Polfuss, in Waukesha, Wis., on June 9, 1915. He began his career as a musician, billing himself as Red Hot Red or Rhubarb Red. He toured with the popular Chicago band Rube Tronson and His Texas Cowboys and led the house band on WJJD radio in Chicago.

In the mid-1930s he joined Fred Waring’s Pennsylvanians and soon moved to New York to form the Les Paul Trio, with Jim Atkins and bassist Ernie Newton.

Meanwhile, he had made his first attempt at audio amplification at age 13. Unhappy with the amount of volume produced by his acoustic guitar, Paul tried placing a telephone receiver under the strings. Although this worked to some extent, only two strings were amplified and the volume level was still too low.

By placing a phonograph needle in the guitar, all six strings were amplified, which proved to be much louder. Paul was playing a working prototype of the electric guitar in 1929.

His work on taping techniques began in the years after World War II, when Bing Crosby gave him a tape recorder. Drawing on his earlier experimentation with his homemade record-cutting machines, Paul added an additional playback head to the recorder. The result was a delayed effect that became known as tape echo.

Tape echo gave the recording a more “live” feel and enabled the user to simulate different playing environments.

Paul’s next “crazy idea” was to stack together eight mono tape machines and send their outputs to one piece of tape, stacking the recording heads on top of each other. The resulting machine served as the forerunner to today’s multitrack recorders.

In 1954, Paul commissioned Ampex to build the first eight-track tape recorder, later known as “Sel-Sync,” in which a recording head could simultaneously record a new track and play back previous ones.

He had met Ford, then known as Colleen Summers, in the 1940s while working as a studio musician in Los Angeles. For seven years in the 1950s, Paul and Ford broadcast a TV show from their home in Mahwah, N.J. Ford died in 1977, 15 years after they divorced.

In recent years, even after his illness in early 2006, Paul played Monday nights at New York night spots. Such stars as Led Zeppelin’s Jimmy Page, Dire Straits’ Mark Knopfler, Bruce Springsteen and Eddie Van Halen came to pay tribute and sit in with him.

“It’s where we were the happiest, in a `joint,'” he said in a 2000 interview with the AP. “It was not being on top. The fun was getting there, not staying there — that’s hard work.”

Dr. Quake’s Genome

Okay, so news that a technique has been found to sequence a genome for less than $50 000 US–a process which used to cost billions–is pretty cool. The fact that the Stanford engineer who came up with the idea’s name is Stephen R. Quake? Priceless.

Dr. Quake says that the technique–which he first used to sequence his own genome on the cheap–“will democratize access to the fruits of the genome revolution” by enabling many labs and hospitals to decode whole human genomes. Affordability no doubt moves us one step closer to the age of genetically-tailored medical treatments.

So, like I said, all very impressive and an advance that will doubtless help countless people…but can anyone tell me why a guy named Dr. Quake is working in the field of genetics?

Don’t get me wrong–he’s obviously very talented and quite skilled in his chosen field. But Dr. Quake? Shouldn’t he be designing doomsday machines to fight Superman? Some kind of ray that will crack the Earth in two or something?

I mean, the guy’s name is Dr. Quake–you couldn’t come up with a better supervillain name if you tried…

– S.

Aliette de Bodard Rules the World!

I’m beyond thrilled to congratulate my friend and fellow WOTFian Aliette de Bodard on her three-book publishing deal with Angry Robot, a new imprint from HarperCollins dedicated to the best in modern adult science fiction, fantasy and everything in between.

Aliette has turned her WOTF-winning story “Obsidian Shards” into a novel, titled Servant of the Underworld–a fantasy mystery set in Aztec times. In this alternate world, the gods are real and stalk the temples, demanding sacrifice. Amidst the bloodletting, a serial killer appears to be getting away with murder–but how do you find a murderer in a world where the streets themselves are awash with blood? Aliette promises that the book contains “ghostly jaguars, bloodthirsty gods, and fingernail-eating monsters.”

Servant of the Underworld will publish in the UK, Canada, the United States and Australia in Spring 2010. The other two books, both set in the same world, will follow in due course.

Perhaps the wildest thing about the deal is how it all came together:

Stuck an extra day in at the Calgary airport after last November’s World Fantasy, Aliette happened to meet fellow strandees John Berlyne and Marc Gascoigne. They got talking and the pair had Aliette pitch her novel right there. Well, in the best traditions of a Hollywood movie it worked, because she landed an agent–from the new literary agency Zeno–and a publisher in Angry Robot thanks to that meeting.

I couldn’t be more thrilled for her. If you’re attending WorldCon in Montreal this weekend (alas, I have a friend’s wedding and can’t go) be sure to look for her–she’ll be the one walking on air 🙂

– S.

Toronto Book Launch for “Winds of Dune” by Brian Herbert and Kevin J. Anderson

Some cool news for Toronto SF fans:

Brian Herbert and Kevin J. Anderson will be doing a book launch for their latest Dune book, Winds of Dune, at the Merril Collection of Science Fiction, Speculation and Fantasy on Tuesday, August 18, 2009.

“Winds of Dune” is the second book in the four-part Heroes of Dune series, which chronicles events between Frank Herbert’s “Dune Messiah” (1969) and “Children of Dune” (1976).

Books will be available (courtesy of Bakka-Phoenix Books) for signing by the authors.

Kevin Anderson is a super nice guy, so I recommed attending the launch. I’m looking forward to meeting Brian Herbert, too. He’s one of the Writers of the Future judges I didn’t get to meet the year that I won.

The Merril Collection is on the 3rd floor of the Lillian H. Smith library, 239 College St., and the book launch starts at 7 PM.

And remember: for those of you who can’t wait until the 18th to buy your copy at the launch, Winds of Dune is available through booksellers everywhere as of tomorrow, August 4.
See you at the launch!

– S.

Charles N. Brown, 1937-2009

I’ve been too lax in posting of late to return with such sad news: Locus publisher, editor, and co-founder Charles N. Brown, 72, died peacefully in his sleep July 12, 2009 on his way home from Readercon.

Like many a Writers of the Future alum before me, I got to know Charles briefly during the awards week in 2007. Charles knew something funny and/or incriminating about everyone is SF and was a featured speaker each year at WOTF, giving each new class insights into the SF field from his decades of first-hand experience of the genre (he was, after all, there in New York when it all began…)

The year I was at WOTF, Charles was recipient of the Hubbard Lifetime Achievement Award. He gave what I later found out was his traditional speech about what it takes to succeed in the industry and warning this newest crop of SF writers away from a life spent toiling in the sci-fi mines…

“Most of you will fail. Most of you won’t make it,” he said, to some nervous chuckling from the writers.

Sean Williams and Steve Savile later told me that reactions amongst their cohorts had been the same, with many people shocked by what Charles had to say. They said we’d actually had kind of a gentle version of his usual speech–perhaps he was tempering things this year given his impending award.

While this continued to trouble some over the next few days, others (myself included) were able not to dismiss it but, in essence, be determined that we’d prove Charles wrong.

Charles was very generous with his time at WOTF, hanging out with the writers long after many others had gone to bed. He spent many hours by the pool with us that final Saturday night, telling jokes, sharing stories…

I saw and spoke to him again briefly a few months later at World Fantasy–he spoke of looking forward to his knee-replacement surgery–but my personal favorite experience with Charles in the brief time I knew him was the Friday night of WOTF, after the award ceremony.

We’d returned to the hotel and I, still shell-shocked from my grand prize win, wandered down to the bar…only to discover it was CLOSED!

Charles Brown and Amelia Beamer (also of Locus) were there, and just as we arrived Rome and Sean Williams retired to their rooms. “Come have a seat by me,” Charles said to me. Cool.

Though the bar was closed, Amelia turned out to have snuck in a micky of Hennessey, which Charles poured into a dirty glass for me.

It might have been the best drink I’d ever had. It tasted like victory. It was a very sweet gesture on his part and I will always remember that night and that moment when I think of him.


Charles Brown receives the 2007 Hubbard Lifetime Achievement Award.(Photo courtesy Galaxy Press/WOTF)

– S.

The Book of Exodi Now Available!

I’m very pleased to announce that The Book of Exodi, a collection of nineteen stories on the theme of mass exodus, which includes my new story “Cladistics”, is now available.

This collection (to which Harry Turtledove contributes an introduction and story) is the first print-on-demand book I’ve ever been involved in. It’s been a very pleasant experience working with Michael Eidson, the editor/manager of the publisher, Eposic Diversions. And since I keep hearing that POD and the so-called “long tail” is the future, well, I thought I’d get in on the ground floor 🙂

Order your copy direct from the printer, CreateSpace, here or get it via Amazon here.

Enjoy!

– S.

The Manchester Fiction Prize 2009

<b>The Manchester Fiction Prize 2009</b>

First prize: £10,000
Deadline for entries: 7th August 2009
Entry fee: £15

Under the direction of Poet Laureate Carol Ann Duffy, the Writing
School at Manchester Metropolitan University is launching The
Manchester Fiction Prize – a new literary competition celebrating
excellence in creative writing.

The Manchester Fiction Prize is open internationally and will award a
cash prize of £10,000* to the writer of the best short story
submitted. The competition is open to entrants aged 16 or over; there
is no upper age limit.

A bursary for study at MMU will also be awarded to an entrant aged
18-25 as part of the Manchester Young Writer of the Year Award*.
Eligible entrants are asked to indicate on the entry form if they
would like to be considered for the Manchester Young Writer of the
Year Award in addition to the main prize.

All entrants are asked to submit a complete short story of up to 5,000
words in length. The story can be on any subject, and written in any
style, but must be new work, not published or submitted for
consideration elsewhere. The competition will be judged by
distinguished novelists and short story writers Sarah Hall, M. John
Harrison and Nicholas Royle.

The Manchester Fiction Prize celebrates the substantial cultural and
literary achievements of Manchester, building on the work of MMU's
Writing School and enhancing the city's reputation as one of Europe's
most adventurous and creative spaces. The prizes will be awarded at a
gala ceremony, held as part of the 2009 Manchester Literature
Festival.

You can enter online by going to: http://www.manchesterwritingcompetition.co.uk

If you would like a printed entry pack for postal submission, or if
you have any queries, please contact:

James Draper
Project Manager: Writing School
Department of English
Manchester Metropolitan University
Telephone: +44 (0) 161 247 1787
E-mail: j.draper@mmu.ac.uk

*Terms and Conditions apply. See
http://www.manchesterwritingcompetition.co.uk for full details.

Dan Brown’s Print-run to Block Out the Sun

I posted recently about Audrey Niffenegger getting a $5 million advance for her new novel and thought that was pretty impressive.

Well, not to be out-done, news that Dan Brown’s new book, The Lost Symbol, will have a first printing of 5 million copies, a record for his publisher, Doubleday.

A FIRST PRINTING of 5 million copies! Good grief. I assume that means the unit cost on each book will be about an eighth of a cent… Don’t worry–you’ll still have to pay $35 for the hardcover 😉

– S.